HDAC6 ligand-4
HDAC6 ligand-4 is a targeted ligand for histone deacetylase 6 (HDAC6). HDAC6 ligand-4 can serve as a target protein ligand for TO-1187 (HY-173266) and is used in studies related to PROTAC synthesis.
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- Formule: C17H17N3O2
- Masse moléculaire:295.34
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
[1]|
HDAC6 |
In Vitro
HDAC6 ligand-4 acts as a target protein ligand for TO-1187 (HY-173266), a selective HDAC6 PROTAC degrader (DC50 = 5.81 nM). TO-1187 promotes the ubiquitination and degradation of HDAC6[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Masse moléculaire 295.34
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Formule C17H17N3O2
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SMILES
O=C(C1=CC=C(C=C1)CN(CC2=CN=CC=C2)CC#C)NO
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)