IDOR-4
Based on 1 Customer Validation
IDOR-4 is a type IV CFTR corrector. IDOR-4 restores F508del-CFTR trafficking to the cell surface.
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- Pureté : 96.98%
- CAS No.: 2839901-24-3
- Formule: C44H51F3N12O7
- Masse moléculaire:916.95
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
In Vitro
IDOR-4 (0.1-1000 nM, 24 h) restores F508del-CFTR function (YFP quenching assay), indicated by the increased F508del-CFTR C-band expression in CFBE cells, reflecting the trafficking to the cell surface[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 2839901-24-3
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Appearance Solid
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Masse moléculaire 916.95
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Formule C44H51F3N12O7
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Color White to off-white
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SMILES
CC1=C2N=CC=CC2=C3C(N[C@@H](CC(N([C@H](C(N([C@@H](C(N[C@@H](COC3=C1)CC4=CC=CC=C4)=O)CC5=NC(C(F)(F)F)=NO5)C)=O)CC(C)C)C)=O)C(NCCN6N=NC(C7CC7)=N6)=O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
DMSO : ≥ 250 mg/mL (272.64 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (276 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0906 mL | 5.4529 mL | 10.9057 mL | 27.2643 mL |
| 5 mM | 0.2181 mL | 1.0906 mL | 2.1811 mL | 5.4529 mL | |
| 10 mM | 0.1091 mL | 0.5453 mL | 1.0906 mL | 2.7264 mL | |
| 15 mM | 0.0727 mL | 0.3635 mL | 0.7270 mL | 1.8176 mL | |
| 20 mM | 0.0545 mL | 0.2726 mL | 0.5453 mL | 1.3632 mL | |
| 25 mM | 0.0436 mL | 0.2181 mL | 0.4362 mL | 1.0906 mL | |
| 30 mM | 0.0364 mL | 0.1818 mL | 0.3635 mL | 0.9088 mL | |
| 40 mM | 0.0273 mL | 0.1363 mL | 0.2726 mL | 0.6816 mL | |
| 50 mM | 0.0218 mL | 0.1091 mL | 0.2181 mL | 0.5453 mL | |
| 60 mM | 0.0182 mL | 0.0909 mL | 0.1818 mL | 0.4544 mL | |
| 80 mM | 0.0136 mL | 0.0682 mL | 0.1363 mL | 0.3408 mL | |
| 100 mM | 0.0109 mL | 0.0545 mL | 0.1091 mL | 0.2726 mL |
IDOR-4 Related Classifications
HY-158002 Related Classifications
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