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Cat. No.: HY-157560

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KDRLKZ-3

(Synonyms: 1NEG)

KDRLKZ-3 is a selective E3 ligase. KDRLKZ-3 is a ligand for KLHDC2 with a IC₅₀ value of 4.1 μM in the alphaLISA experiment.

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Formule: C₂₃H₃₀N₄O₆
Masse moléculaire:458.51

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

KDRLKZ-3 Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

KDRLKZ-3 is a selective E3 ligase. KDRLKZ-3 is a ligand for KLHDC2 with a IC₅₀ value of 4.1 μM in the alphaLISA experiment^[1].

Voir tous les produits spécifiques à Isoform Ligands for E3 Ligase :

Chemical Information

Masse moléculaire 458.51
Formule C₂₃H₃₀N₄O₆
SMILES

O=C(OCCOC)N(CC1)CC(N(C2=O)C3=CN(C(C=C3)=O)CC(N)=O)=C1C=C2C(C)CC
Synonyms

1NEG
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Hickey CM, et al. Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules. Nat Struct Mol Biol. 2024 Jan 4. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Activité biologique
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Chemical Information
Pureté et documentation
Références

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KDRLKZ-3

Voir tous les produits spécifiques à Isoform Ligands for E3 Ligase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

KDRLKZ-3 Related Classifications

HY-157560 Related Classifications