Lanperisone
Lanperisone is a novel oral muscle relaxant with anticancer activity. Lanperisone produces non-apoptotic cell death by inhibiting monosynaptic and polysynaptic reflex potentials. Lanperisone is also believed to play an important role in the dysregulation of iron metabolism and antioxidant systems to modulate processes associated with ischemic stroke.
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- CAS No.: 116287-14-0
- Formule: C15H18F3NO
- Masse moléculaire:285.30
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MEF | IC50 |
4 μM
Compound: 7
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Cytotoxicity against MEF harboring KRAS G12D mutant by ATP-based cell viability assay
Cytotoxicity against MEF harboring KRAS G12D mutant by ATP-based cell viability assay
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[PMID: 23566315] |
| MEF | IC50 |
4 μM
Compound: 7
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Antiproliferative activity against mouse MEF cells expressing KRAS G12D mutant assessed as reduction in cell viability incubated for 48 hrs by CellTiter-Glo luminescent assay
Antiproliferative activity against mouse MEF cells expressing KRAS G12D mutant assessed as reduction in cell viability incubated for 48 hrs by CellTiter-Glo luminescent assay
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[PMID: 36332549] |
| MEF | IC50 |
4 μM
Compound: Lanperisone
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Cytotoxicity against MEF expressing K-rasG12D after 48 hrs by CellTiter-Glo assay
Cytotoxicity against MEF expressing K-rasG12D after 48 hrs by CellTiter-Glo assay
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[PMID: 22297109] |
Chemical Information
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CAS No. 116287-14-0
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Masse moléculaire 285.30
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Formule C15H18F3NO
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SMILES
O=C([C@@H](CN1CCCC1)C)C2=CC=C(C=C2)C(F)(F)F
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Synonyms
NK433 free base
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Lanperisone Related Classifications
HY-119325 Related Classifications
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