MC1
MC1 is a potent NLRP3 inhibitor with a KD value of 19.3 nM. MC1 shows no cytotoxicity. MC1 ameliorates cognitive deficits without eliciting adverse effects and shows an absence of hepatotoxicity. MC1 has the potential for the research of Alzheimer's disease (AD).
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Formule: C23H23N3O6S2
- Masse moléculaire:501.58
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
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NLRP3 19.3 nM (Kd) |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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Masse moléculaire 501.58
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Formule C23H23N3O6S2
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SMILES
O=C(NS(C1=CC(C(C)(O)C)=CS1)(=O)=O)NC2=C(C3=CC=C([N+]([O-])=O)C=C3)C=CC4=C2CCC4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)