MDI-2268
Based on 1 Customer Validation
MDI-2268 is an inhibitor of plasma kallikrein inhibitor 1 (PAI-1). MDI-2268 has good antithrombotic properties and regulates blood coagulation and fibrinolysis process by enhancing fibrinolysis. MDI-2268 can be used in research areas such as deep vein thrombosis.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 99.73%
- CAS No.: 1609176-50-2
- Formule: C10H10F3N3O3
- Masse moléculaire:277.20
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
MDI-2268 (1 mM, 3 days) prevents Paneth cell defects and apoptosis in Atg16l1 T300A organoids[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Atg16l1 T300A organoids
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Concentration:1 mM
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Incubation Time:3 days
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Result:Reduced the cleaved caspase 3.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Mouse electrolytic IVC models[1]
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Dosage:1.5-3 mg/kg
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Administration:ip, every 8 hours for 6 doses
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Result:Reduced the thrombus weight.
Chemical Information
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CAS No. 1609176-50-2
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Appearance Solid
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Masse moléculaire 277.20
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Formule C10H10F3N3O3
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Color White to off-white
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SMILES
O=C(NN)C(NCC1=CC=CC(OC(F)(F)F)=C1)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : 166.67 mg/mL (601.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6075 mL | 18.0375 mL | 36.0750 mL | 90.1876 mL |
| 5 mM | 0.7215 mL | 3.6075 mL | 7.2150 mL | 18.0375 mL | |
| 10 mM | 0.3608 mL | 1.8038 mL | 3.6075 mL | 9.0188 mL | |
| 15 mM | 0.2405 mL | 1.2025 mL | 2.4050 mL | 6.0125 mL | |
| 20 mM | 0.1804 mL | 0.9019 mL | 1.8038 mL | 4.5094 mL | |
| 25 mM | 0.1443 mL | 0.7215 mL | 1.4430 mL | 3.6075 mL | |
| 30 mM | 0.1203 mL | 0.6013 mL | 1.2025 mL | 3.0063 mL | |
| 40 mM | 0.0902 mL | 0.4509 mL | 0.9019 mL | 2.2547 mL | |
| 50 mM | 0.0722 mL | 0.3608 mL | 0.7215 mL | 1.8038 mL | |
| 60 mM | 0.0601 mL | 0.3006 mL | 0.6013 mL | 1.5031 mL | |
| 80 mM | 0.0451 mL | 0.2255 mL | 0.4509 mL | 1.1273 mL | |
| 100 mM | 0.0361 mL | 0.1804 mL | 0.3608 mL | 0.9019 mL |
MDI-2268 Related Classifications
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