Methyl helicterate
Methyl helicterate is a triterpenoid, that can be isolated from Helicteres angustifolia (Sterculiaceae). Methyl helicterate inhibits hepatic stellate cell activation and promotes cell apoptosis through downregulating the ERK1/2 signaling pathway.
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- CAS No.: 102637-02-5
- Formule: C40H56O6
- Masse moléculaire:632.87
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Stockage:
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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ERK1 |
ERK2 |
Chemical Information
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CAS No. 102637-02-5
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Masse moléculaire 632.87
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Formule C40H56O6
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SMILES
CC1([C@H](CC[C@@]2([C@]3(CC[C@@]4([C@]5([C@@H](CC[C@@]5(CC[C@]4([C@@]3(CC[C@@]12[H])C)COC(C6=CC=CC=C6)=O)C(OC)=O)C(C)=C)[H])[H])[H])C)OC(C)=O)C
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Wei Y, et al. Methyl helicterate inhibits hepatic stellate cell activation through downregulating the ERK1/2 signaling pathway. J Cell Biochem. 2019 Sep;120(9):14936-14945. [Content Brief]
[2]. Huang Q, et al. Effect and mechanism of methyl helicterate isolated from Helicteres angustifolia (Sterculiaceae) on hepatic fibrosis induced by carbon tetrachloride in rats. J Ethnopharmacol. 2012 Oct 11;143(3):889-95. [Content Brief]
[3]. Chen W, et al. Pregnane, coumarin and lupane derivatives and cytotoxic constituents from Helicteres angustifolia. Phytochemistry. 2006 May;67(10):1041-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Methyl helicterate Related Classifications
HY-125522 Related Classifications
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