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Cat. No.: HY-N11554

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(-)-Codonopsine

(-)-Codonopsine is an alkaloid with antibacterial activity. (-)-Codonopsine can be used in research related to Staphylococcus aureus and Escherichia coli infections.

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CAS No.: 26989-20-8
Formule: C₁₄H₂₁NO₄
Masse moléculaire:267.32

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

(-)-Codonopsine Chemical Structure

CAS No.: 26989-20-8

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Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Bioz

Activité biologique

Description

(-)-Codonopsine is an alkaloid with antibacterial activity. (-)-Codonopsine can be used in research related to Staphylococcus aureus and Escherichia coli infections^[1].

In Vitro

(-)-Codonopsine (0.5-1024 μg/mL; 18 h) inhibits Staphylococcus aureus (ATCC 29213) with a MIC of 32 μg/mL, Escherichia coli (ATCC 25922) with a MIC of 64 μg/mL^[1].
(-)-Codonopsine (0.5-1024 μg/mL; 18 h) shows no activity (MIC >1024 μg/mL) against Klebsiella pneumoniae (ATCC 700603), Proteus mirabilis (ATCC 14153), Pseudomonas aeruginosa (ATCC 27853), Acinetobacter baumannii (clinical isolate), and Candida albicans (ATCC 10231)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 26989-20-8
Masse moléculaire 267.32
Formule C₁₄H₂₁NO₄
SMILES

O[C@@H]1[C@H](N([C@@H]([C@H]1O)C)C)C2=CC(OC)=C(C=C2)OC
Structure Classification
- Alkaloids
- Pyrrole Alkaloids
Initial Source
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. El-Nezhawy AOH, et al. Design and total synthesis of (-)-codonopsinine, (-)-codonopsine and codonopsinine analogues by O-(2-oxopyrrolidin-5-yl)trichloroacetimidate as amidoalkylating agent with improved antimicrobial activity via solid lipid nanoparticle formulations. Bioorg Med Chem. 2019;27(7):1263-1273. [Content Brief]

[2]. Hideo Iida, et al. Stereochemical revision and absolute configuration of codonopsinine. Tetrahedron Letters. Volume 27, Issue 44, 1986, Pages 5393-5396.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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