ML-10
Based on 1 Customer Validation
ML-10 is a small molecule apoptosis probe. Due to the presence of fluorine atoms, ML-10 can be radiolabeled with 18F isotopes and can be used for apoptosis positron emission tomography imaging studies. ML-10 is selectively taken up and accumulated in apoptotic cells, while being excluded from live or necrotic cells. In addition, the uptake of ML-10 is associated with apoptotic features such as caspase activation, Annexin-V binding, and disruption of mitochondrial membrane potential.
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- Pureté : 95.0%
- CAS No.: 1216897-16-3
- Formule: C9H15FO4
- Masse moléculaire:206.21
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
Essai clinique
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1216897-16-3
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Appearance Solid
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Masse moléculaire 206.21
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Formule C9H15FO4
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Color White to off-white
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SMILES
O=C(O)C(C)(CCCCCF)C(O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
DMSO : 100 mg/mL (484.94 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.8494 mL | 24.2471 mL | 48.4943 mL | 121.2356 mL |
| 5 mM | 0.9699 mL | 4.8494 mL | 9.6989 mL | 24.2471 mL | |
| 10 mM | 0.4849 mL | 2.4247 mL | 4.8494 mL | 12.1236 mL | |
| 15 mM | 0.3233 mL | 1.6165 mL | 3.2330 mL | 8.0824 mL | |
| 20 mM | 0.2425 mL | 1.2124 mL | 2.4247 mL | 6.0618 mL | |
| 25 mM | 0.1940 mL | 0.9699 mL | 1.9398 mL | 4.8494 mL | |
| 30 mM | 0.1616 mL | 0.8082 mL | 1.6165 mL | 4.0412 mL | |
| 40 mM | 0.1212 mL | 0.6062 mL | 1.2124 mL | 3.0309 mL | |
| 50 mM | 0.0970 mL | 0.4849 mL | 0.9699 mL | 2.4247 mL | |
| 60 mM | 0.0808 mL | 0.4041 mL | 0.8082 mL | 2.0206 mL | |
| 80 mM | 0.0606 mL | 0.3031 mL | 0.6062 mL | 1.5154 mL | |
| 100 mM | 0.0485 mL | 0.2425 mL | 0.4849 mL | 1.2124 mL |
ML-10 Related Classifications
HY-76573 Related Classifications
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