Niludipine
Niludipine (Bay a 7168) is an orally active calcium channel blocker and vasodilator with antihypertensive effects. Niludipine can improve early fatal ventricular arrhythmias induced by acute myocardial ischemia in rats. Niludipine can reduce left ventricular systolic and diastolic loads during pacing-induced angina pectoris. Niludipine can be used in the research of cardiovascular diseases such as coronary heart disease and myocardial ischemia.
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- CAS No.: 22609-73-0
- Formule: C25H34N2O8
- Masse moléculaire:490.55
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
Chemical Information
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CAS No. 22609-73-0
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Masse moléculaire 490.55
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Formule C25H34N2O8
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SMILES
CCCOCCOC(C1=C(C)NC(C)=C(C(OCCOCCC)=O)C1C2=CC([N+]([O-])=O)=CC=C2)=O
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Synonyms
Bay a 7168
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Kurita A, et al. Effects of new calcium channel blocker of niludipine on the coronary hemodynamics, diastolic properties, and metabolic responses to tachycardia stress in patients with coronary disease. Cathet Cardiovasc Diagn. 1982;8(4):373-81. [Content Brief]
[2]. Fagbemi O, et al. Suppression by orally-administered nifedipine, nisoldipine and niludipine of early, life-threatening ventricular arrhythmias resulting from acute myocardial ischaemia. Br J Pharmacol. 1981 Sep;74(1):12-4. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Niludipine Related Classifications
HY-106458 Related Classifications
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