NMB-1
NMB-1 is a conopeptide analogue. NMB-1 selectively inhibits sustained mechanically activated currents in sensory neurons (IC50: 1 μM). NMB-1 inhibits mechanical pain. NMB-1 can be used for research of hearing and pressure-evoked pain.
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- CAS No.: 2843557-76-4
- Formule: C111H164N36O21S4
- Masse moléculaire:2466.98
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Chemical Information
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CAS No. 2843557-76-4
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Masse moléculaire 2466.98
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Formule C111H164N36O21S4
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Sequence
Phe-Asn-Trp-Arg-Cys-Cys-Leu-Ile-Pro-Cys-Arg-Arg-Asn-His-Lys-Lys-Phe-Phe-Cys-NH2 (Disulfide bridge: Cys5-Cys19, Cys6-Cys10)
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Sequence Shortening
FNWRCCLIPCRRNHKKFFC-NH2 (Disulfide bridge: Cys5-Cys19, Cys6-Cys10)
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Drew LJ, et al. High-threshold mechanosensitive ion channels blocked by a novel conopeptide mediate pressure-evoked pain. PLoS One. 2007 Jun 13;2(6):e515. [Content Brief]
[2]. Raouf R, et al. Inhibition of somatosensory mechanotransduction by annexin A6. Sci Signal. 2018 Jun 19;11(535):eaao2060. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NMB-1 Related Classifications
HY-P5163 Related Classifications
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