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Cat. No.: HY-155185

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NMDA receptor antagonist 7

NMDA receptor antagonist 7 (Compound (S)-10a) is GluN2B subunit-selective NMDA Receptor antagonist, with an K_i of 93 nM and an IC₅₀ of 72 nM. NMDA receptor antagonist 7 can be used for research of neurodegenerative diseases.

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CAS No.: 3033746-13-0
Formule: C₂₂H₂₇N₃O
Masse moléculaire:349.47

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

NMDA receptor antagonist 7 Chemical Structure

CAS No.: 3033746-13-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

IC₅₀ & Target

72 nM (GluN2B subunit)^[1]

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Chemical Information

CAS No. 3033746-13-0
Masse moléculaire 349.47
Formule C₂₂H₂₇N₃O
SMILES

O[C@@H](CCN1CCC(CC2=CC=CC=C2)CC1)C3=CC(C=NN4)=C4C=C3
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Lüken J, et al. Indazole as a Phenol Bioisostere: Structure-Affinity Relationships of GluN2B-Selective NMDA Receptor Antagonists. J Med Chem. 2023 Aug 24;66(16):11573-11588. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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NMDA receptor antagonist 7

Voir tous les produits spécifiques à Isoform iGluR

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

NMDA receptor antagonist 7 Related Classifications

HY-155185 Related Classifications