NS2359
NS2359 (GSK372475) is a serotonin-norepinephrine-dopamine triple reuptake inhibitor. NS2359 is used for research on depression.
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- CAS No.: 195875-68-4
- Formule: C16H21Cl2NO
- Masse moléculaire:314.25
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
NS2359 simultaneously blocks three monoamine transporters and increases the levels of three types of neurotransmitters in the synaptic cleft to regulate mood, cognition and reward pathways.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 195875-68-4
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Masse moléculaire 314.25
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Formule C16H21Cl2NO
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SMILES
COC[C@@H]1[C@@H](C2=CC(Cl)=C(C=C2)Cl)C[C@@]3([H])N([C@]1([H])CC3)C
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Synonyms
GSK372475
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Learned S, et al. Efficacy, safety, and tolerability of a triple reuptake inhibitor GSK372475 in the treatment of patients with major depressive disorder: two randomized, placebo- and active-controlled clinical trials. Journal of psychopharmacology (Oxford, England). 2012 May;26(5):653-62. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)