Oleylphosphocholine
Oleylphosphocholine is an orally active antifungal and antiparasitic agent. Oleylphosphocholine is promising for research of invasive fungal diseases (e.g., aspergillosis) and visceral leishmaniasis.
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- CAS No.: 257925-44-3
- Formule: C23H48NO4P
- Masse moléculaire:433.61
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 257925-44-3
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Masse moléculaire 433.61
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Formule C23H48NO4P
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SMILES
CCCCCCCCC/C=C\CCCCCCCOP([O-])(OCC[N+](C)(C)C)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Dawson R, et al. Phase I Single Ascending Dose and Food Effect Study in Healthy Adults and Phase I/IIa Multiple Ascending Dose Study in Patients with Pulmonary Tuberculosis to Assess Pharmacokinetics, Bactericidal Activity, Tolerability, and Safety of OPC-167832. Antimicrob Agents Chemother. 2023 Jun 15;67(6):e0147722. [Content Brief]
[2]. Paulussen C, et al. Efficacy of oleylphosphocholine (OlPC) in vitro and in a mouse model of invasive aspergillosis. Mycoses. 2015 Mar;58(3):127-32. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)