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Opemalirsen

(Synonyms: AZD2373, ION-972190)

Opemalirsen is an antisense oligonucleotide targeted to apolipoprotein L1 (APOL1). It is used for the study of Kidney disorders.

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  • Opemalirsen Chemical Structure
    Opemalirsen Chemical Structure
CAS No.: 2639853-99-7
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  • Opemalirsen Chemical Structure
    Opemalirsen Chemical Structure DNA, d(P-thio)([2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-α-L-mannofurano]m5rU-(3'→4')-[2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-α-L-mannofurano]m5rU-(3'→4')-[2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-α-L-mannofurano](3'→4')m5rU-T-G-T-A-A-G-T-G-m5C-(3'→4')-[2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-α-L-mannofurano]rA-(3'→4')-[2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-α-L-mannofurano]rA-(3'→4')-[2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-α-L-mannofurano]m5rC-[2'-O-(2-methoxyethyl)]m5rC)
    1/16
  • DNA, d(P-thio)([2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-α-L-mannofurano]m5rU-(3'→4')-[2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-α-L-mannofurano]m5rU-(3'→4')-[2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-α-L-mannofurano](3'→4')m5rU-T-G-T-A-A-G-T-G-m5C-(3'→4')-[2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-α-L-mannofurano]rA-(3'→4')-[2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-α-L-mannofurano]rA-(3'→4')-[2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-α-L-mannofurano]m5rC-[2'-O-(2-methoxyethyl)]m5rC)