PAQ
PAQ (Compound 4c) is a quinoxaline derivative. PAQ is an orally active neuroprotective agent, which targets dopamine (DA) neurons and activates reticulum endoplasmic ryanodine receptor (RyR) channels, without effects on glia cells.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 943902-10-1
- Formule: C14H11N3
- Masse moléculaire:221.26
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Voir tous les produits spécifiques à Isoform Calcium Channel
More
Activité biologique
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Neurotoxin MPTP (HY-15608) induced dopamine depletion in Parkinson disease in C57BL/6 mice[1]
-
Dosage:25-50 mg/kg
-
Administration:p.o. for 11 days
-
Result:Reduced levels of striatal DA and DOPAC+HVA/DA ratios. Maintained dendritic network in midbrain tissue sections in TH+ neurons.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
-
CAS No. 943902-10-1
-
Masse moléculaire 221.26
-
Formule C14H11N3
-
SMILES
NC1=CC=C2N=CC(C3=CC=CC=C3)=NC2=C1
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PAQ Related Classifications
HY-138806 Related Classifications
Powered by Bioz