pCR8
pCR8 is a prodrug of CR8 (HY-18340). pCR8 is amphiphilic and can self-assemble into nanoparticles. pCR8 can release CR8 under the action of high concentration of H2O2 in the tumor microenvironment. CR8 is a molecular glue degrader that can effectively degrade cell cycle-related proteins and has antitumor activity. pCR8 can be used in the research of tumors such as breast cancer.
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- Formule: C32H36BN7O5
- Masse moléculaire:609.48
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Chemical Information
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Masse moléculaire 609.48
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Formule C32H36BN7O5
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SMILES
CC[C@@H](COC(OCC1=CC=C(B(O)O)C=C1)=O)NC2=NC(NCC(C=C3)=CC=C3C4=CC=CC=N4)=C(N=CN5C(C)C)C5=N2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)