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Cat. No.: HY-169115

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PD-0299685

PD-0299685 is a potent Ca²⁺ channel α2δ ligand. PD-0299685 is promising for research of refractory genito-urinary pain and interstitial cystitis/bladder pain syndrome.

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CAS No.: 313651-33-1
Formule: C₁₀H₂₁NO₂
Masse moléculaire:187.28

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

PD-0299685 Chemical Structure

CAS No.: 313651-33-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

PD-0299685 is a potent Ca²⁺ channel α2δ ligand. PD-0299685 is promising for research of refractory genito-urinary pain and interstitial cystitis/bladder pain syndrome^[1]^[2].

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Essai clinique

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 313651-33-1
Masse moléculaire 187.28
Formule C₁₀H₂₁NO₂
SMILES

CCC[C@@H](C)C[C@H](CN)CC(O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Nickel JC, et al. Investigation of a Ca2+ channel α2δ ligand for the treatment of interstitial cystitis: results of a randomized, double-blind, placebo controlled phase II trial. J Urol. 2012 Sep;188(3):817-23.

[2]. Nickel J C, et al. 821 A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PHASE IIA TRIAL OF A CA2+ CHANNEL α2Δ LIGAND, PD-0299685, FOR THE TREATMENT OF INTERSTITIAL CYSTITIS/BLADDER PAIN SYNDROME[J]. The Journal of Urology, 2012, 187(4S): e335-e335.

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Activité biologique
- Description
- Essai clinique
Chemical Information
Pureté et documentation
Références

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PD-0299685

Voir tous les produits spécifiques à Isoform Calcium Channel

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

PD-0299685 Related Classifications

HY-169115 Related Classifications