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Cat. No.: HY-120302

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PD 140376

PD 140376 is a potent antagonist for the cholecystokininB/gastrin receptor, with K_i values of 0.18 nM and 0.21 nM in guinea-pig cortex and gastric gland membranes, respectively.

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CAS No.: 149027-97-4
Formule: C₃₃H₄₀N₄O₅
Masse moléculaire:572.69

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

PD 140376 Chemical Structure

CAS No.: 149027-97-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

PD 140376 is a potent antagonist for the cholecystokininB/gastrin receptor, with K_i values of 0.18 nM and 0.21 nM in guinea-pig cortex and gastric gland membranes, respectively^[1].

Voir tous les produits spécifiques à Isoform Cholecystokinin Receptor :

CCKAR
CCKBR

Chemical Information

CAS No. 149027-97-4
Masse moléculaire 572.69
Formule C₃₃H₄₀N₄O₅
SMILES

O=C(C[C@H](CC1=CC=C(C=C1)N)NC([C@@](C)(CC2=CNC3=C2C=CC=C3)NC(OC4C5CC(CC4C6)CC6C5)=O)=O)O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. J C Hunter, et al. [3H]PD 140376: a novel and highly selective antagonist radioligand for the cholecystokininB/gastrin receptor in guinea pig cerebral cortex and gastric mucosa. Mol Pharmacol. 1993 Apr;43(4):595-602 [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
Chemical Information
Pureté et documentation
Références

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PD 140376

Voir tous les produits spécifiques à Isoform Cholecystokinin Receptor