PLAP-IN-1
PLAP-IN-1 is a selective PLAP inhibitor with an IC50 of 0.032 μM. PLAP-IN-1 acts as a tumor-targeting agent; its fluorescein-conjugated derivative specifically binds to PLAP-positive tumor cells in vitro and targets cervical cancer in mouse xenograft models. PLAP-IN-1 can be used in the research of cervical cancer and ovarian cancer.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 2857113-78-9
- Formule: C25H21Cl2N3O5
- Masse moléculaire:514.36
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
PLAP-IN-1 (compound 16) potently inhibits purified PLAP with an IC50 of 32 nM, and exhibits high selectivity toward tissue-nonspecific alkaline phosphatase (TNAP)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2857113-78-9
-
Masse moléculaire 514.36
-
Formule C25H21Cl2N3O5
-
SMILES
ClC1=C(OC)C(Cl)=CC(C2=CC=CC(C[C@@H](NC(C3=NNC(C4=CC=C(C)O4)=C3)=O)C(O)=O)=C2)=C1
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)