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Cat. No.: HY-W957364

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Pomalidomide-C2-Br

Pomalidomide-C2-Br is an E3 Ligase Ligand (HY-14658) and linker (HY-W007731) conjugate. Pomalidomide-C2-Br can be used to synthesize PROTAC AR Degrader-8 (HY-170329).

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CAS No.: 2940940-74-7
Formule: C₁₅H₁₄BrN₃O₄
Masse moléculaire:380.19

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Pomalidomide-C2-Br Chemical Structure

CAS No.: 2940940-74-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

Pomalidomide-C2-Br is an E3 Ligase Ligand (HY-14658) and linker (HY-W007731) conjugate. Pomalidomide-C2-Br can be used to synthesize PROTAC AR Degrader-8 (HY-170329)^[1].

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Chemical Information

CAS No. 2940940-74-7
Masse moléculaire 380.19
Formule C₁₅H₁₄BrN₃O₄
SMILES

O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCBr)=CC=C3)=O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Ha S, et al. Discovery of a highly potent, N-terminal domain-targeting degrader of AR-FL/AR-V7 for the treatment of prostate cancer. Eur J Med Chem. 2025 Jan 15;282:117079. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Pomalidomide-C2-Br

Voir tous les produits spécifiques à Isoform E3 Ligase Ligand-Linker Conjugates

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Pomalidomide-C2-Br Related Classifications

HY-W957364 Related Classifications