NH2-C5-NH-Boc
Based on 1 Customer Validation
NH2-C5-NH-Boc (PROTAC Linker 23) is an alkyl chain-based PROTAC linker can be used in the synthesis of PROTACs.
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- Pureté: 99.59%
- CAS No.: 51644-96-3
- Formule: C10H22N2O2
- Masse moléculaire:202.29
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Stockage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Activité biologique
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Alkyl-Chain |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 51644-96-3
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Appearance Liquid (Density: 0.972 g/cm3)
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Masse moléculaire 202.29
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Formule C10H22N2O2
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Color Colorless to light yellow
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SMILES
O=C(OC(C)(C)C)NCCCCCN
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Synonyms
PROTAC Linker 23
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvant et solubilité
Ethanol : 100 mg/mL (494.34 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (267 KB)
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SDS (477 KB)
- English - EN (477 KB)
- Français - FR (477 KB)
- Deutsch - DE (477 KB)
- Norwegian - NO (477 KB)
- Español - ES (477 KB)
- Swedish - SV (477 KB)
- Italian - IT (477 KB)
- Korean - KR (477 KB)
- Portuguese - PT (477 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol | 1 mM | 4.9434 mL | 24.7170 mL | 49.4340 mL | 123.5850 mL |
| 5 mM | 0.9887 mL | 4.9434 mL | 9.8868 mL | 24.7170 mL | |
| 10 mM | 0.4943 mL | 2.4717 mL | 4.9434 mL | 12.3585 mL | |
| 15 mM | 0.3296 mL | 1.6478 mL | 3.2956 mL | 8.2390 mL | |
| 20 mM | 0.2472 mL | 1.2358 mL | 2.4717 mL | 6.1792 mL | |
| 25 mM | 0.1977 mL | 0.9887 mL | 1.9774 mL | 4.9434 mL | |
| 30 mM | 0.1648 mL | 0.8239 mL | 1.6478 mL | 4.1195 mL | |
| 40 mM | 0.1236 mL | 0.6179 mL | 1.2358 mL | 3.0896 mL | |
| 50 mM | 0.0989 mL | 0.4943 mL | 0.9887 mL | 2.4717 mL | |
| 60 mM | 0.0824 mL | 0.4119 mL | 0.8239 mL | 2.0597 mL | |
| 80 mM | 0.0618 mL | 0.3090 mL | 0.6179 mL | 1.5448 mL | |
| 100 mM | 0.0494 mL | 0.2472 mL | 0.4943 mL | 1.2358 mL |