EphB3
EphB3 shares with EphB2 a central role in intestinal architecture, helping to segregate proliferative crypt cells from differentiated epithelium through forward signaling from ephrin-B ligands. Its expression extends to the immune system, where EphB3 on thymocytes and T cells participates in thymocyte selection, T-cell activation and adhesion, and it has been examined as a marker in leukemias and lymphomas. In the nervous system, EphB3 contributes to hippocampal plasticity and to regeneration after injury. Testis and colorectal tissue are additional sites of expression, with altered EphB3 levels reported in colorectal and prostate cancers. Recombinant EphB3 supports epithelial and immunological Eph research.
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EphB3 Protéines Recombinantes (6)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formule: Human
- Masse moléculaire: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
