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Cat. No.: HY-106083

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Quazolast

(Synonyms: RHC 3988)

Quazolast (RHC 3988) is a orally active mast cell stabilizer. Quazolast also is a potent mediator release inhibitor. Quazolast reduces the gastric damage. Quazolast has the potential for the research of gastric ulcers.

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CAS No.: 86048-40-0
Formule: C₁₂H₇ClN₂O₃
Masse moléculaire:262.65

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Quazolast Chemical Structure

CAS No.: 86048-40-0

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Activité biologique
- Description
- In Vivo
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

In Vivo

Quazolast (0.2, 1, 5 mg/kg; p.o.) reduces the gastric damage in rats induced by absolute ethanol (0.9 mg/kg)^[1].
Quazolast (3.1, 6.3, 12.5, 25 mg/kg; p.o.) reduces the gastric damage associated with 0.6 N HC1 administration^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

150 g Male Sprague Dawley rat^[1]
Dosage:

0.2, 1, 5 mg/kg
Administration:

P.o.
Result:

Decreased the rat gastric mucosa damage in a dose dependent manner and reduced the gastric ulcer index (68%) at 5 mg/kg in rat induced by absolute ethanol (0.9 mg/kg).

Chemical Information

CAS No. 86048-40-0
Masse moléculaire 262.65
Formule C₁₂H₇ClN₂O₃
SMILES

COC(C1=NC2=CC(Cl)=C3C(N=CC=C3)=C2O1)=O
Synonyms

RHC 3988
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Fitzpatrick LR, et al. Gastroprotective and ulcer healing profile of the mast cell stabilizer quazolast in rats. Agents Actions. 1991 Jul;33(3-4):330-6. [Content Brief]

[2]. Dave NK, et al. A controlled, double-blind study of the effect of quazolast on nasal challenge with ragweed antigen. Ann Allergy. 1990 Oct;65(4):298-302. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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