SCH 39304
SM-8668 is an effective orally active antifungal agent, with median effective doses (ED50) of 0.18, 3.7, and 5.9 mg/kg for systemic candidiasis, aspergillosis, and cryptococcosis in mice, respectively. Pharmacokinetic studies in mice and rats indicate that SM-8668 has a long half-life and a high total exposure. SM-8668 can be used in anti-infective research.
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- CAS No.: 120924-80-3
- Formule: C13H15F2N3O3S
- Masse moléculaire:331.34
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 120924-80-3
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Masse moléculaire 331.34
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Formule C13H15F2N3O3S
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SMILES
CS([C@@H](C)[C@](O)(C1=C(C=C(C=C1)F)F)CN2C=NC=N2)(=O)=O
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Synonyms
SM-8668
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SCH 39304 Related Classifications
HY-105110 Related Classifications
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