41 Results for "

TRAIL-R

" in MedChemExpress (MCE) Product Catalog:
Products (41)

41 Results for "TRAIL-R" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P99934
CAS No.: 1820660-69-2
Synonyms: ABBV-621

Domaines de recherche:  

Cancer

Eftozanermin alfa (ABBV-621) is a tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R) agonist. Eftozanermin alfa is a fusion protein consisting of a mutant immunoglobulin G1-Fc linked to 2 single-chain trimers of TRAIL. Eftozanermin alfa induces apoptosis in tumor cells by activation of death receptors (DR4 receptor and DR5 receptor) with Kds of 780 nM and 635 nM. Eftozanermin alfa can be used for the research of multiple solid and heme malignancies .
loading...
    loading...
Cat. No.: HY-P99260
CAS No.: 896731-82-1
Synonyms: AMG 655; TRAIL-R2 mAb; Human Anti-TNFRSF10B Recombinant Antibody

Target:  

TNF Receptor

Domaines de recherche:  

Cancer

Conatumumab (AMG 655) is a human monoclonal agonist antibody against human death receptor 5 (DR5, TRAILR2) (Kd: 1 nM for the long form of DR5, 0.8 nM for the short form of DR5). Conatumumab induces apoptosis via caspase activation. Conatumumab can be used in the research of cancers. .
loading...
    loading...
Cat. No.: HY-148875
CAS No.: 2247398-68-9
Pureté:  99.78%
Domaines de recherche:  

Cancer

Py-MAA-Val-Cit-PAB-MMAE is a drug-Linker conjugates for ADC, which is composed of MMAE (HY-15162) and Py-MAA-Val-Cit-PAB linked. Py-MAA-Val-Cit-PAB-MMAE can be used to synthesize Zapadcine-3a, which targeting TRAILR2. Zapadcine-3a has broad-spectrum anti-tumor activity, and can specifically kill TRAILR2-positive tumors .
loading...
    loading...
Cat. No.: HY-P99299
CAS No.: 845816-02-6
Synonyms: HGS-ETR 2; ETR2-ST01

Target:  

Apoptosis

Domaines de recherche:  

Cancer

Lexatumumab (HGS-ETR 2) is a human agonistic TRAIL receptor 2 (TRAIL-R2, DR5, APO-2) IgG4κ type monoclonal antibody. Lexatumumab induces apoptosis in malignant mesothelioma. Lexatumumab can be used for malignant pleural mesothelioma (MPM) research .
loading...
    loading...
Cat. No.: HY-P99270
CAS No.: 918127-53-4
Synonyms: CS-1008; Anti-Human TRAIL-R2 Recombinant Antibody

Target:  

Apoptosis

Domaines de recherche:  

Cancer

Tigatuzumab (CS-1008) is a humanized IgG1 monoclonal antibody targets death receptor 5 (DR5). Tigatuzumab induces cell apoptosis of cancer cells and inhibits tumor growth in vivo. Tigatuzumab can be used for the research of cancer .
loading...
    loading...
Cat. No.: HY-P99265
CAS No.: 658052-09-6
Synonyms: HGS-ETR1; Anti-Human TNFRSF10A Recombinant Antibody

Target:  

Inhibitory Antibodies

Domaines de recherche:  

Cancer

Mapatumumab (HGS-ETR1) is a fully human IgG1 agonistic monoclonal antibody that targets tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1). Mapatumumab can be used for the research of cancer .
loading...
    loading...
Cat. No.: HY-P78529
Pureté:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: DR4; CD261; TNFRSF10A; TRAIL-R; APO2; TRAIL R1; MGC9365
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P78219
Pureté:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: DR4; CD261; TNFRSF10A; TRAIL-R; APO2; TRAIL R1; MGC9365
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P84855
Synonyms: DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4

Host:  

Mouse

Application:  

WB, ELISA

Reactivity:  

Human, Monkey

loading...
    loading...
Cat. No.: HY-P84856
Synonyms: DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4

Host:  

Mouse

Application:  

WB, ELISA

Reactivity:  

Human, Mouse

loading...
    loading...
Cat. No.: HY-P84855A
Synonyms: DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4

Host:  

Mouse

Application:  

WB, ELISA

Reactivity:  

Human, Monkey

loading...
    loading...
Cat. No.: HY-P84856A
Synonyms: DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4

Host:  

Mouse

Application:  

WB, ELISA

Reactivity:  

Human, Mouse

loading...
    loading...
Cat. No.: HY-P78567
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF10B; TRAILR2; TRAIL-R2; CD262; DR5; KILLER; TRICK2; ZTNFR9; TRICKB
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P74497
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member 10B; CD262; TRAIL-R2; DR5; KILLER; TRAILR2; ZTNFR9
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P74498
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member 10B; CD262; TRAIL-R2; DR5; KILLER; TRAILR2; ZTNFR9
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P72779
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member 10B; Death receptor 5; TRAIL-R2; CD262; TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P76863
Pureté:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member 10D; DcR2; TRAIL-R4; CD264; TRUNDD
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P72439
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member 10D; DcR2; TRAIL receptor 4; TRAIL-R4; CD264; TNFRSF10D; DCR2; TRAILR4; TRUNDD
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P76865
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member 10D; DcR2; TRAIL-R4; CD264; TRUNDD
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P76864
Pureté:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member 10D; DcR2; TRAIL-R4; CD264; TRUNDD
Species:  
Source:  
loading...
    loading...