Secaubryenol
Secaubryenol is a class of 3,4-secocycloartane triterpenes isolated from Coussarea macrophylla. Secaubryenol does not display any cytotoxic effect at a dose of 10 μg/mL.
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- CAS No.: 925932-08-7
- Formule: C30H48O3
- Masse moléculaire:456.70
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BT-474 | IC50 |
>5 μg/mL
Compound: 4
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Cytotoxicity against human BT474 cells after 3 days by MTT assay
Cytotoxicity against human BT474 cells after 3 days by MTT assay
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[PMID: 20028108] |
| HepG2 | IC50 |
>5 μg/mL
Compound: 4
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Cytotoxicity against human HepG2 cells after 3 days by MTT assay
Cytotoxicity against human HepG2 cells after 3 days by MTT assay
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[PMID: 20028108] |
| SW-620 | IC50 |
>5 μg/mL
Compound: 4
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Cytotoxicity against human SW620 cells after 3 days by MTT assay
Cytotoxicity against human SW620 cells after 3 days by MTT assay
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[PMID: 20028108] |
Secaubryenol exhibits IC50 value over 100 μM against tumor cell lines (MCF-7 (breast cancer cells, ER (estrogen receptor) positive), MDA (breast cancer cells, ER negative), PC-3 (prostate cancer cells), and HeLa (cervical cancer cells))[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 925932-08-7
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Masse moléculaire 456.70
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Formule C30H48O3
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SMILES
[H][C@]1([C@H](C)CC/C=C(C)/C)CC[C@]2(C)[C@]1(C)CC[C@]34[C@@]2([H])CC[C@@H](C(CO)=C)[C@@]3(CCC(O)=O)C4
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Grougnet R, et al. Cytotoxic 3,4-seco-cycloartane triterpenes from the exudate of Gardenia tubifera. J Nat Prod. 2006 Dec;69(12):1711-4. [Content Brief]
[2]. Gilardoni G, et al. New 3,4-Secocycloartane and 3,4-Secodammarane Triterpenes from the Ecuadorian Plant Coussarea macrophylla. Chem Biodivers. 2015 Jun;12(6):946-54. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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