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Cat. No.: HY-149712

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Spermatinamine

Spermatinamine is a novel alkaloid with a bromotyrosyl-spermine-bromotyrosyl sequence, and a natural ICMT inhibitor. Spermatinamine can be isolated from the Australian sponge Pseudoceratina.

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CAS No.: 1001438-81-8
Formule: C₃₂H₄₄Br₄N₆O₆
Masse moléculaire:928.34

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Spermatinamine Chemical Structure

CAS No.: 1001438-81-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Spermatinamine is a novel alkaloid with a bromotyrosyl-spermine-bromotyrosyl sequence, and a natural ICMT inhibitor. Spermatinamine can be isolated from the Australian sponge Pseudoceratina^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
DU-145	IC₅₀	1.6 μM Compound: 1	Cytotoxicity against human DU145 cells assessed as viable cells after 24 hrs by Solid plate-based spot culture growth inhibition assay Cytotoxicity against human DU145 cells assessed as viable cells after 24 hrs by Solid plate-based spot culture growth inhibition assay	[PMID: 26874403]
MCF7	IC₅₀	1.6 μM Compound: 1	Cytotoxicity against human MCF7 cells assessed as viable cells after 24 hrs by Solid plate-based spot culture growth inhibition assay Cytotoxicity against human MCF7 cells assessed as viable cells after 24 hrs by Solid plate-based spot culture growth inhibition assay	[PMID: 26874403]

Chemical Information

CAS No. 1001438-81-8
Masse moléculaire 928.34
Formule C₃₂H₄₄Br₄N₆O₆
SMILES

BrC1=C(OC)C(Br)=CC(C/C(C(NCCCN(C)CCCCN(C)CCCNC(/C(CC2=CC(Br)=C(OC)C(Br)=C2)=N/O)=O)=O)=N\O)=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Buchanan MS et al. Spermatinamine, the first natural product inhibitor of isoprenylcysteine carboxyl methyltransferase, a new cancer target. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6860-3. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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