Sulfathiourea
Sulfathiourea is an inhibitor of Pneumocystis carinii dihydropteroate synthetase (dihydropteroate synthetase), with an IC50 of 0.022 μM and a Ki of 16.5 nM. Sulfathiourea blocks folate biosynthesis by inhibiting the enzyme that links 7,8-dihydro-6-hydroxymethylpterin pyrophosphate with p-aminobenzoic acid to form dihydropteroate. Sulfathiourea can be used in research related to *Pneumocystis carinii* pneumonia.
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- CAS No.: 515-49-1
- Formule: C7H9N3O2S2
- Masse moléculaire:231.29
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
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Help & FAQs
Activité biologique
Description
In Vitro
Sulfathiourea potently inhibits recombinant *Pneumocystis carinii* dihydropteroate synthase, with an IC50 of 22 nM and a Ki of 16.5 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 515-49-1
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Masse moléculaire 231.29
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Formule C7H9N3O2S2
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SMILES
O=S(=O)(NC(=S)N)C1=CC=C(N)C=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Sulfathiourea Related Classifications
HY-100010 Related Classifications
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