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Sutimlimab

(Synonyms: BIVV009; IPN-009; TNT009)
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Sutimlimab is a humanized monoclonal IgG4 antibody. Sutimlimab inhibits complement protein component 1, s subcomponent (C1s). Sutimlimab blocks C3 and C4 activation. Sutimlimab can be used for the research of cold agglutinin disease and complement-mediated hemolytic uremic syndrome.

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  • Pureté: 98.81%
  • CAS No.: 2049079-64-1
  • Masse moléculaire:144.8 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Sutimlimab
  • Experimental Validation Results for Sutimlimab
  • Experimental Validation Results for Sutimlimab
  • Sutimlimab Chemical Structure
    Sutimlimab Chemical Structure
CAS No.: 2049079-64-1
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Sutimlimab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG4 kappa

  • 1/16

    Immobilized C1s/Complement component C1s Protein, Human can bind Sutimlimab. The EC50 for this effect is 16.31 ng/mL.

  • 1/16

    Flow Cytometry analysis of A549 cells labelling C1s (red) with Sutimlimab (anti-C1s) (HY-P99050). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa (HY-P99003, blue) was used as the isotype control.

  • Sutimlimab Chemical Structure
    1/16
  • Sutimlimab
  • Immobilized C1s/Complement component C1s Protein, Human can bind Sutimlimab. The EC50 for this effect is 16.31 ng/mL.
  • Flow Cytometry analysis of A549 cells labelling C1s (red) with Sutimlimab (anti-C1s) (HY-P99050). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa (HY-P99003, blue) was used as the isotype control.