Thiol-PEG2-acid
Based on 1 Customer Validation
Thiol-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- Pureté : 96.0%
- CAS No.: 1379649-73-6
- Formule: C7H14O4S
- Masse moléculaire:194.25
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Voir tous les produits spécifiques à Isoform PROTAC Linkers
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Activité biologique
Description
IC50 & Target
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PEGs |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1379649-73-6
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Appearance Liquid (Density: 1.173±0.06 g/cm3)
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Masse moléculaire 194.25
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Formule C7H14O4S
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Color Colorless to light yellow
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SMILES
O=C(O)CCOCCOCCS
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvant et solubilité
In Vitro:
DMSO : 100 mg/mL (514.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (266 KB)
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SDS (620 KB)
- English - EN (620 KB)
- Français - FR (620 KB)
- Deutsch - DE (620 KB)
- Norwegian - NO (620 KB)
- Español - ES (620 KB)
- Swedish - SV (620 KB)
- Italian - IT (620 KB)
- Korean - KR (620 KB)
- Portuguese - PT (620 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.1480 mL | 25.7400 mL | 51.4801 mL | 128.7001 mL |
| 5 mM | 1.0296 mL | 5.1480 mL | 10.2960 mL | 25.7400 mL | |
| 10 mM | 0.5148 mL | 2.5740 mL | 5.1480 mL | 12.8700 mL | |
| 15 mM | 0.3432 mL | 1.7160 mL | 3.4320 mL | 8.5800 mL | |
| 20 mM | 0.2574 mL | 1.2870 mL | 2.5740 mL | 6.4350 mL | |
| 25 mM | 0.2059 mL | 1.0296 mL | 2.0592 mL | 5.1480 mL | |
| 30 mM | 0.1716 mL | 0.8580 mL | 1.7160 mL | 4.2900 mL | |
| 40 mM | 0.1287 mL | 0.6435 mL | 1.2870 mL | 3.2175 mL | |
| 50 mM | 0.1030 mL | 0.5148 mL | 1.0296 mL | 2.5740 mL | |
| 60 mM | 0.0858 mL | 0.4290 mL | 0.8580 mL | 2.1450 mL | |
| 80 mM | 0.0644 mL | 0.3218 mL | 0.6435 mL | 1.6088 mL | |
| 100 mM | 0.0515 mL | 0.2574 mL | 0.5148 mL | 1.2870 mL |
Thiol-PEG2-acid Related Classifications
HY-138524 Related Classifications
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