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Tilavonemab

(Synonyms: ABBV-8E12; C2N-8E12)
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Tilavonemab (ABBV-8E12) is a humanized anti-tau monoclonal antibody that binds to amino acids 25-30 near the N-terminus of the tau protein. Tilavonemab can block the ability of human and mouse neurons to uptake tau aggregates. Tilavonemab can be used for research on Alzheimer’s disease and other tauopathies.

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  • Pureté: 99.59%
  • CAS No.: 2096513-89-0
  • Masse moléculaire:145 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Tilavonemab
  • Experimental Validation Results for Tilavonemab
  • Experimental Validation Results for Tilavonemab
  • Tilavonemab Chemical Structure
    Tilavonemab Chemical Structure
CAS No.: 2096513-89-0
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Tilavonemab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG4 kappa

  • 1/16

    Immobilized Human Tau Protein (His Tag) can bind Tilavonemab. The EC50 for this effect is 2.182 ng/mL.

  • 1/16

    Flow cytometric analysis of 1.5X106 SHSY5Y cells labeling Tilavonemab (HY-P99163, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa, Isotype Control (HY-P99003, blue) was used as the isotype control.

  • Tilavonemab Chemical Structure
    1/16
  • Tilavonemab
  • Immobilized Human Tau Protein (His Tag) can bind Tilavonemab. The EC50 for this effect is 2.182 ng/mL.
  • Flow cytometric analysis of 1.5X106 SHSY5Y cells labeling Tilavonemab (HY-P99163, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa, Isotype Control (HY-P99003, blue) was used as the isotype control.