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Cat. No.: HY-N15637

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Torularhodin

Torularhodin is a carotenoid with anti-cancer activity. Torularhodin induces apopotsis of tumor cells and can be used for the study of prostate cancer.

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CAS No.: 514-92-1
Formule: C₄₀H₅₂O₂
Masse moléculaire:564.84

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (261 KB)

Torularhodin Chemical Structure

CAS No.: 514-92-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vivo
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Torularhodin is a carotenoid with anti-cancer activity. Torularhodin induces apopotsis of tumor cells and can be used for the study of prostate cancer^[1].

In Vivo

Torularhodin (9-18 mg/kg; p.o; every day; for 10 weeks) inhibits the growth of prostate cancer in nude mice and suggest that such an action is associated the apoptosis of tumor cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Four to six-week-old BALB/c nude mice (male, 18-22 g) were subcutaneously injected with PC-3 cells (5 × 10⁵ cells)^[1]
Dosage:

9 mg/kg, 18 mg/kg
Administration:

p.o; every day; 2 weeks before transplantation; 7 weeks after transplantation
Result:

Lowered the mean number of tumors.
Tumor degeneration, apoptosis and necrosis presented at the end of the experiment.
Increased the mRNA expressions of caspase-3, 8 and 9 in tumor tissues.
Showed Bcl-2 expression of the control group was higher than that of the carotenoid-treated group while the expression of Bax was lower than the carotenoid-treated group.

Chemical Information

CAS No. 514-92-1
Masse moléculaire 564.84
Formule C₄₀H₅₂O₂
SMILES

OC(/C(C)=C/C=C/C(C)=C/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)=O
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
- Microorganisms
Rhodotorula rubra
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (261 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Du C, et al. The suppression of torulene and torularhodin treatment on the growth of PC-3 xenograft prostate tumors. Biochem Biophys Res Commun. 2016 Jan 22;469(4):1146-52. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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