CAIX/CAXII-IN-2
CAIX/CAXII-IN-2 (compound 23) is a CAIX/CAXII inhibitor, with Ki values of 8.9 nM and 5.3 nM for CAIX/CAXII, respectively. CAIX/CAXII-IN-2 can be used in cancer research.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 3067730-65-5
- Formel: C16H14N4O2S
- Molecular Weight:326.37
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
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hCA IX 8.9 nM (Ki) |
hCA XII 5.3 nM (Ki) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MDA-MB-231 | IC50 |
38.8 μM
Compound: 23
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Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell growth incubated for 72 hrs in the presence of hypoxic condition by cytofluorimetric analysis
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell growth incubated for 72 hrs in the presence of hypoxic condition by cytofluorimetric analysis
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[PMID: 38911163] |
| U-87MG ATCC | IC50 |
34 μM
Compound: 23
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Antiproliferative activity against human U-87MG cells assessed as reduction in cell growth incubated for 72 hrs in the presence of hypoxic condition by cytofluorimetric analysis
Antiproliferative activity against human U-87MG cells assessed as reduction in cell growth incubated for 72 hrs in the presence of hypoxic condition by cytofluorimetric analysis
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[PMID: 38911163] |
CAIX/CAXII-IN-2 (compound 23) (0-1000 μM, 72h) inhibits the proliferation of MDA-MB-231 and U87MG cells, with the IC50 values of 38.8 μM and 34 μM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 3067730-65-5
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Molecular Weight 326.37
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Formel C16H14N4O2S
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SMILES
O=S(C1=CC=C(C2=NC(N)=NC(C3=CC=CC=C3)=C2)C=C1)(N)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
CAIX/CAXII-IN-2 Related Classifications
HY-159132 Related Classifications
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