1020719-45-2
Chemical Structure
Formoterol-d6
Synonym(s): (±)Formoterol-d6
- CAS No.: 1020719-45-2
- Formula:C19H18D6N2O4
- Molecular Weight:350.44
IUPAC Name: N-(2-hydroxy-5-(1-hydroxy-2-((1-(4-methoxyphenyl)propan-2-yl-1,1,2,3,3,3-d6)amino)ethyl)phenyl)formamide
InChIKey: BPZSYCZIITTYBL-CNHGSDQPSA-N
SMILES: C(CNC(C(C1=CC=C(OC)C=C1)([2H])[2H])(C([2H])([2H])[2H])[2H])(O)C2=CC(NC=O)=C(O)C=C2
Biological Activity: Formoterol-d6 ((±)Formoterol-d6) is the d6-labeled Formoterol (HY-B0010B). Formoterol is a selective β2-adrenoceptor agonist. Formoterol is at least as β2-adrenoceptor selective as Salbutamol (HY-B1067) and Terbutaline (HY-B0802A). Formoterol abolishs the contraction induced by Acetylcholine in bronchioles. Formoterol can be used for the research of chronic obstructive pulmonary disease and bronchial asthma[1][2].
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Formoterol-d6 | Formoterol-d6 ((±)Formoterol-d6) is the d6-labeled Formoterol (HY-B0010B). Formoterol is a selective β2-adrenoceptor agonist. Formoterol is at least as β2-adrenoceptor selective as Salbutamol (HY-B1067) and Terbutaline (HY-B0802A). Formoterol abolishs the contraction induced by Acetylcholine in bronchioles. Formoterol can be used for the research of chronic obstructive pulmonary disease and bronchial asthma. | |||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Arun JJ, Lodha R, Kabra SK. Bronchodilatory effect of inhaled budesonide/formoterol and budesonide/salbutamol in acute asthma: a double-blind, randomized controlled trial.BMC Pediatr. 2012 Mar 7;12:21. [Content Brief]
