105102-22-5
105102-22-5
Chemical Structure
Mometasone
- CAS No.: 105102-22-5
- Formula:C22H28Cl2O4
- Molecular Weight:427.36
IUPAC Name: (8S,9R,10S,11S,13S,14S,16R,17R)-9-chloro-17-(2-chloroacetyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
InChIKey: QLIIKPVHVRXHRI-CXSFZGCWSA-N
SMILES: Cl[C@@]1([C@]2(C=C3)C)[C@](CCC2=CC3=O)([H])[C@@](C[C@@H](C)[C@]4(O)C(CCl)=O)([H])[C@]4(C)C[C@@H]1O
Biological Activity: Mometasone is an inhaled glucocorticoid. Mometasone can be used in mild asthma with a low sputum eosinophil level. Mometasone has the potential for the research of chronic hand eczema and rhinosinusitis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Mometasone | 99.46% | Mometasone is an inhaled glucocorticoid. Mometasone can be used in mild asthma with a low sputum eosinophil level. Mometasone has the potential for the research of chronic hand eczema and rhinosinusitis. | ||||||||||||||||||||
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Mometasone (Standard) | 99.72% | Mometasone (Standard) is the analytical standard of Mometasone. This product is intended for research and analytical applications. Mometasone is an inhaled glucocorticoid. Mometasone can be used in mild asthma with a low sputum eosinophil level. Mometasone has the potential for the research of chronic hand eczema and rhinosinusitis. | ||||||||||||||||||||
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Mometasone-d5 | Mometasone-d5 is the deuterium labeled Mometasone. | |||||||||||||||||||||
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Beclometasone dipropionate | 99.80% | Beclometasone dipropionate, the proagent of Beclometasone, is an orally active and potent glucocorticoid recepter agonist. Beclometasone dipropionate acts via a glucocorticoid receptor and suppresses inflammation and hyperproliferation. Beclometasone dipropionate can be used for asthma . | ||||||||||||||||||||
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Beclometasone dipropionate monohydrate | Beclometasone dipropionate monohydrate, the proagent of Beclometasone, is an orally active and potent glucocorticoid recepter agonist. Beclometasone dipropionate monohydrate acts via a glucocorticoid receptor and suppresses inflammation and hyperproliferation. Beclometasone dipropionate monohydrate can be used for asthma . | |||||||||||||||||||||
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Beclomethasone 17-propionate (Standard) | ≥98% | Beclomethasone 17-propionate (Standard) is the analytical standard of Beclomethasone 17-propionate. This product is intended for research and analytical applications. Beclomethasone 17-propionate (Beclomethasone-17-monopropionate), an active metabolite of Beclomethasone dipropionate (HY-13571), is a glucocorticoid receptor (GR) agonist. Beclomethasone 17-propionate exhibits greater affinity for GR than Beclomethasone dipropionate. Beclomethasone 17-propionate effectively suppresses cytokine production in chronic obstructive pulmonary disease (COPD) lung macrophages. | ||||||||||||||||||||
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Beclomethasone 21-propionate | Beclomethasone 21-propionate is a class of biochemical reagents for the study of glycobiology. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It deals with carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the role of glycans in biological systems. The field is closely related to basic research, biomedicine and biotechnology. | |||||||||||||||||||||
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Beclometasone | 99.87% | Beclometasone (Beclomethasone) is a prototype glucocorticoid receptor agonist. | ||||||||||||||||||||
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Dexamethasone 9,11-epoxide (Standard) | ≥98% | Dexamethasone 9,11-epoxide (Standard) is the analytical standard of Dexamethasone 9,11-epoxide (HY-N0348). This product is intended for research and analytical applications. Dexamethasone 9,11-epoxide is an intermediate. Dexamethasone 9,11-epoxide can be used in the preparation of Dexamethasone (HY-14648). Dexamethasone 9,11-epoxide can be used in the research of inflammatory and immune diseases. | ||||||||||||||||||||
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Betamethasone impurity 5 | Betamethasone impurity 5 is an impurity of Betamethasone. | |||||||||||||||||||||
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Dexamethasone impurity 1 | Dexamethasone impurity 1 is an impurity of Dexamethasone (HY-14648). | |||||||||||||||||||||
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Beclometasone dipropionate impurity 1 | Beclometasone dipropionate impurity 1 (Beclomethasone 21-acetate 17-propionate) is an impurity of Beclometasone dipropionate. | |||||||||||||||||||||
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Betamethasone valerate impurity 1 | Betamethasone valerate impurity 1 is an impurity of Betamethasone valerate (HY-B0727). | |||||||||||||||||||||
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References
- [1]. Veien NK, et al. Long-term, intermittent treatment of chronic hand eczema with mometasone furoate. Br J Dermatol. 1999 May;140(5):882-6. [Content Brief]
- [2]. Lazarus SC, et al. Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level. N Engl J Med. 2019 May 23;380(21):2009-2019. [Content Brief]
