112-79-8
Chemical Structure
Elaidic acid
- CAS No.: 112-79-8
- Formula:C18H34O2
- Molecular Weight:282.46
IUPAC Name: (E)-octadec-9-enoic acid
InChIKey: ZQPPMHVWECSIRJ-MDZDMXLPSA-N
SMILES: CCCCCCCC/C=C/CCCCCCCC(O)=O
Biological Activity: Elaidic acid is an orally active trans fatty acid. Elaidic acid enhances the stemness of colorectal cancer cells by activating the Wnt/ERK1/2 pathway, thereby promoting cell proliferation, invasion and metastasis, and inhibiting apoptosis. Elaidic acid also inhibits the growth of Lactobacillus and alters the cell surface hydrophobicity of Lactobacillus. Elaidic acid reduces basal 2-deoxyglucose uptake in muscle cells and adipocytes. Elaidic acid can be used in research on colorectal cancer, insulin and other related areas[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Elaidic acid | 99.81% | Elaidic acid is an orally active trans fatty acid. Elaidic acid enhances the stemness of colorectal cancer cells by activating the Wnt/ERK1/2 pathway, thereby promoting cell proliferation, invasion and metastasis, and inhibiting apoptosis. Elaidic acid also inhibits the growth of Lactobacillus and alters the cell surface hydrophobicity of Lactobacillus. Elaidic acid reduces basal 2-deoxyglucose uptake in muscle cells and adipocytes. Elaidic acid can be used in research on colorectal cancer, insulin and other related areas. | ||||||||||||||||||||
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Elaidic acid (Standard) | 99.75% | Elaidic acid (Standard) is the analytical standard of Elaidic acid. This product is intended for research and analytical applications. Elaidic acid is the major trans fat found in hydrogenated vegetable oils and can be used as a pharmaceutical solvent. | ||||||||||||||||||||
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Elaidic acid-d9 | 99.0% | Elaidic acid-d9 is deuterium labeled Elaidic acid. Elaidic acid is the major trans fat found in hydrogenated vegetable oils and can be used as a pharmaceutical solvent. | ||||||||||||||||||||
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Elaidic acid-d17 | Elaidic acid-d17 is deuterium labeled Elaidic acid. Elaidic acid is the major trans fat found in hydrogenated vegetable oils and can be used as a pharmaceutical solvent. | |||||||||||||||||||||
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- [1]. Ohmori H, et al. Elaidic Acid, a Trans-Fatty Acid, Enhances the Metastasis of Colorectal Cancer Cells. Pathobiology. 2017;84(3):144-151. [Content Brief]
- [2]. Wu Q, et al. Effects of elaidic acid, a predominant industrial trans fatty acid, on bacterial growth and cell surface hydrophobicity of lactobacilli. J Food Sci. 2014;79(12):M2485-M2490. [Content Brief]
- [3]. Granados N, et al. Distinct effects of oleic acid and its trans-isomer elaidic acid on the expression of myokines and adipokines in cell models. Br J Nutr. 2011;105(8):1226-1234. [Content Brief]
