121-79-9
121-79-9
Chemical Structure
Propyl gallate
- CAS. Nr.: 121-79-9
- Formula:C10H12O5
- Molecular Weight:212.20
IUPAC Name: propyl 3,4,5-trihydroxybenzoate
InChIKey: ZTHYODDOHIVTJV-UHFFFAOYSA-N
SMILES: O=C(OCCC)C1=CC(O)=C(O)C(O)=C1
Biological Activity: Propyl gallate is a common food antioxidant. Propyl gallate can inhibit the production of acrolein, glyoxal and methylglyoxal. Propyl gallate exhibits anti-inflammatory, antitumor and cardioprotective activities[1][2][3][4].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Propyl gallate | 99.74% | Propyl gallate is a common food antioxidant. Propyl gallate can inhibit the production of acrolein, glyoxal and methylglyoxal. Propyl gallate exhibits anti-inflammatory, antitumor and cardioprotective activities. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Propyl gallate (Standard) | 99.98% | Propyl gallate (Standard) is the analytical standard of Propyl gallate. This product is intended for research and analytical applications. Propyl gallate is a common food antioxidant. Propyl gallate can inhibit the production of acrolein, glyoxal and methylglyoxal. Propyl gallate exhibits anti-inflammatory, antitumor and cardioprotective activities. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Gallic acid | 99.99% | Gallic acid (3,4,5-Trihydroxybenzoic acid) is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2). Gallic acid has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Gallic acid hydrate (Standard) | 99.86% | Gallic acid (hydrate) (Standard) is the analytical standard of Gallic acid (hydrate). This product is intended for research and analytical applications. Gallic acid (3,4,5-Trihydroxybenzoic acid) hydrate is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2). Gallic acid hydrate has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Ethyl gallate (Standard) | ≥98% | Ethyl gallate (Standard) is the analytical standard of Ethyl gallate. This product is intended for research and analytical applications. Ethyl gallate is a nonflavonoid phenolic compound and also a scavenger of hydrogen peroxide. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Methyl gallate | 99.97% | Methyl gallate is a plant phenolic with antioxidant, anticancer, and anti-inflammatory activities. Methyl gallate also shows bacterial inhibition activity. Methyl gallate also has anti-HIV-1 and HIV-1 enzyme inhibitory activities. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Ethyl 2,4,6-trihydroxybenzoate | Ethyl 2,4,6-trihydroxybenzoate (Benzoic acid, 2,4,6-trihydroxy-, ethyl ester) is a Triterpenoids product that can be isolated from the herbs of Pueraria lobata. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Ethyl Orsellinate | 99.65% | Ethyl orsellinate is a lichen metabolite and a derivative of lecanoric acid with antiproliferative and antitumour activities. Ethyl Orsellinate is against A. salina for the cytotoxic activity with an LC50 of 495 μM. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Ethyl 3,4-dihydroxybenzoate | 99.96% | Ethyl 3,4-dihydroxybenzoate (Protocatechuic acid ethyl ester) is an orally effective, blood-brain barrier-permeable, competitive prolyl hydroxylase (PHD) inhibitor that inhibits the hydroxylation modification of hypoxia-inducible factor (HIF) by PHD. Ethyl 3,4-dihydroxybenzoate stabilizes HIF-1α by inhibiting PHD, activates downstream pathways to induce autophagy and apoptosis of tumor cells, and regulates inflammatory responses, inhibits the NF-κB pathway, improves vascular permeability, and promotes osteoblast differentiation. Ethyl 3,4-dihydroxybenzoate has anti-tumor, anti-hypoxic injury, and bone metabolism regulation effects. It can also be used in the research of cardiovascular protection (such as reducing myocardial ischemic damage), bone tissue engineering (promoting osteogenesis/inhibiting osteoclast differentiation), and prevention and treatment of high-altitude cerebral edema. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Ethyl 3,5-dihydroxybenzoate | 99.57% | Ethyl 3,5-dihydroxybenzoate is an active compound. Ethyl 3,5-dihydroxybenzoate can be used for the research of various biochemical studies. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Methyl 2,4,6-trihydroxybenzoate (Standard) | ≥98% | Methyl 2,4,6-trihydroxybenzoate is a metabolite of 2,4,6-trihydroxybenzoate and exhibits properties as an antioxidant, lipid lowering and anticancer activities. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Ethyl 3,4-dihydroxybenzoate-13C3 | Ethyl 3,4-Dihydroxybenzoate-13C3 (Protocatechuic acid ethyl ester-13C3) is the 13C-labeled Ethyl 3,4-dihydroxybenzoate (HY-W016409). Ethyl 3,4-dihydroxybenzoate (Protocatechuic acid ethyl ester) is an orally effective, blood-brain barrier-permeable, competitive prolyl hydroxylase (PHD) inhibitor that inhibits the hydroxylation modification of hypoxia-inducible factor (HIF) by PHD. Ethyl 3,4-dihydroxybenzoate stabilizes HIF-1α by inhibiting PHD, activates downstream pathways to induce autophagy and apoptosis of tumor cells, and regulates inflammatory responses, inhibits the NF-κB pathway, improves vascular permeability, and promotes osteoblast differentiation. Ethyl 3,4-dihydroxybenzoate has anti-tumor, anti-hypoxic injury, and bone metabolism regulation effects. It can also be used in the research of cardiovascular protection (such as reducing myocardial ischemic damage), bone tissue engineering (promoting osteogenesis/inhibiting osteoclast differentiation), and prevention and treatment of high-altitude cerebral edema. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Cui H, et al. Dual effects of propyl gallate and its methylglyoxal adduct on carbonyl stress and oxidative stress. Food Chem. 2018 Nov 1;265:227-232. [Content Brief]
- [2]. Wang J, et al. Scavenging of Acrolein by Food-Grade Antioxidant Propyl Gallate in a Model Reaction System and Cakes. J Agric Food Chem. 2019 Aug 7;67(31):8520-8526. [Content Brief]
- [3]. Park WH. Propyl gallate induces cell death in human pulmonary fibroblast through increasing reactive oxygen species levels and depleting glutathione. Sci Rep. 2024 Mar 5;14(1):5375. [Content Brief]
- [4]. Park WH. Propyl gallate reduces the growth of lung cancer cells through caspase‑dependent apoptosis and G1 phase arrest of the cell cycle. Oncol Rep. 2020 Dec;44(6):2783-2791. [Content Brief]
