1229-35-2
1229-35-2
Chemical Structure
Methdilazine hydrochloride
- CAS No.: 1229-35-2
- Formula:C18H21ClN2S
- Molecular Weight:332.89
IUPAC Name: 10-((1-methylpyrrolidin-3-yl)methyl)-10H-phenothiazine hydrochloride
InChIKey: IEISBKIVLDXSMZ-UHFFFAOYSA-N
SMILES: CN(CC1)CC1CN2C3=C(C=CC=C3)SC4=C2C=CC=C4.Cl
Biological Activity: Methdilazine hydrochloride is an orally active antibiotic (histamine antagonist). Methdilazine hydrochloride can inhibit various mycobacterium with MIC values at 5-15 μg/mL in vitro and in vivo, which can be used for the research of infectious diseases[1][2].
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Methdilazine hydrochloride | 99.90% | Methdilazine hydrochloride is an orally active antibiotic (histamine antagonist). Methdilazine hydrochloride can inhibit various mycobacterium with MIC values at 5-15 μg/mL in vitro and in vivo, which can be used for the research of infectious diseases. | ||||||||||||||||||||
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Methdilazine hydrochloride (Standard) | ≥98% | Methdilazine hydrochloride (Standard) is the analytical standard of Methdilazine hydrochloride (HY-B1690A). This product is intended for research and analytical applications. Methdilazine hydrochloride is an orally active antibiotic (histamine antagonist). Methdilazine hydrochloride can inhibit various mycobacterium with MIC values at 5-15 μg/mL in vitro and in vivo, which can be used for the research of infectious diseases. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.98
HY-B1690Methdilazine -
Similarity Score 0.91
HY-121282AMepazine hydrochloride -
Similarity Score 0.90
HY-121282Mepazine -
Similarity Score 0.84
HY-121282BMepazine acetate -
Similarity Score 0.76
HY-124626(R)-(+)-Mequitazine -
Similarity Score 0.76
HY-14845Levomequitazine -
Similarity Score 0.76
HY-B2168Mequitazine -
Similarity Score 0.73
HY-115314Mequitamium iodide -
Similarity Score 0.71
HY-B1225RPromazine hydrochloride (Standard) -
Explore the MedChemAI to find more analogs
References
- [1]. A N Chakrabarty, et al. Antimycobacterial activity of methdilazine (Md), an antimicrobic phenothiazine. APMIS. 1993 Jun;101(6):449-54. [Content Brief]
- [2]. Noton K Dutta, et al. Activity of the phenothiazine methdilazine alone or in combination with isoniazid or streptomycin against Mycobacterium tuberculosis in mice. J Med Microbiol. 2009 Dec;58(Pt 12):1667-1668. [Content Brief]
