1. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  2. Histamine Receptor
  3. Mequitazine

Mequitazine  (Synonyms: LM-209)

Cat. No.: HY-B2168 Purity: 99.97%
COA Handling Instructions

Mequitazine is a potent, and long-acting histamine H1 antagonist.

For research use only. We do not sell to patients.

Mequitazine Chemical Structure

Mequitazine Chemical Structure

CAS No. : 29216-28-2

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
USD 55 In-stock
10 mM * 1 mL in DMSO USD 55 In-stock
1 mg USD 23 In-stock
5 mg USD 50 In-stock
10 mg USD 70 In-stock
25 mg USD 110 In-stock
50 mg USD 150 In-stock
100 mg USD 190 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review


Mequitazine is a potent, and long-acting histamine H1 antagonist.

In Vitro

Mequitazine is a potent H1-receptors selective antihistaminic drug widely studied and used for allergic disorders such as hay fever and urticaria[1]. Mequitazine demonstrates significant bactericidal effects against all the tested clinical isolates including Ps. aeruginosa. Its effect against the Gram-positive isolates is more pronounced[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Mequitazine and clemizole antagonize the effect of histamine in guinea-pig ileum competitively. Mequitazine at 107 produces a parallel shift of the dose-response curve to acetylcholine in the rat duodenum. Mequitazine at highest concentration shows anticholinergic activity[3]. Mequitazine inhibits contractile responses to KCl, phenylephrine (PE), 5-hydroxytryptamine (5-HT), and Ca2+ in rat aorta[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight







White to off-white




Room temperature in continental US; may vary elsewhere.

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 16 mg/mL (49.62 mM; Need ultrasonic and warming)

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1011 mL 15.5053 mL 31.0106 mL
5 mM 0.6202 mL 3.1011 mL 6.2021 mL
10 mM 0.3101 mL 1.5505 mL 3.1011 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation

Purity: 99.99%

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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