127-19-5
127-19-5
Chemical Structure
N,N-Dimethylacetamide
Synonym(s): DMAc
- CAS No.: 127-19-5
- Formula:C4H9NO
- Molecular Weight:87.12
IUPAC Name: N,N-dimethylacetamide
InChIKey: FXHOOIRPVKKKFG-UHFFFAOYSA-N
SMILES: CC(N(C)C)=O
Biological Activity: N,N-Dimethylacetamide (DMAc) is an organic solvent with blood-brain transmissibility and an FDA-approved drug excipient. N, N-dimethylacetamide exerts anti-inflammatory activity by inhibiting the NF-κB signaling pathway. N, N-dimethylacetamide can be used in studies of weight gain caused by a high-fat diet and neuroinflammation in Alzheimer's disease[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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N,N-Dimethylacetamide | 99.96% | N,N-Dimethylacetamide (DMAc) is an organic solvent with blood-brain transmissibility and an FDA-approved drug excipient. N, N-dimethylacetamide exerts anti-inflammatory activity by inhibiting the NF-κB signaling pathway. N, N-dimethylacetamide can be used in studies of weight gain caused by a high-fat diet and neuroinflammation in Alzheimer's disease. | ||||||||||||||||||||
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N,N-Dimethylacetamide (Standard) | ≥98% | N,N-Dimethylacetamide (Standard) is the analytical standard of N,N-Dimethylacetamide. This product is intended for research and analytical applications. N,N-Dimethylacetamide (DMAc) is an organic solvent with blood-brain transmissibility and an FDA-approved drug excipient. N, N-dimethylacetamide exerts anti-inflammatory activity by inhibiting the NF-κB signaling pathway. N, N-dimethylacetamide can be used in studies of weight gain caused by a high-fat diet and neuroinflammation in Alzheimer's disease. | ||||||||||||||||||||
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N,N-Dimethylacetamide-d9 | 99.0% | N,N-Dimethylacetamide-d9 is the deuterium labeled N,N-Dimethylacetamide. N,N-Dimethylacetamide (DMAc) is an inexpensive, common aprotic organic solvent. | ||||||||||||||||||||
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References
- [1]. Sundaram S, et al. N,N-dimethylacetamide regulates the proinflammatory response associated with endotoxin and prevents preterm birth. Am J Pathol. 2013 Aug;183(2):422-30. [Content Brief]
- [2]. Wei ZH, et al. N,N-dimethylacetamide targets neuroinflammation in Alzheimer's disease in in-vitro and ex-vivo models. Sci Rep. 2023 May 1;13(1):7077. [Content Brief]
- [3]. Koya JB, et al. FDA-Approved Excipient N, N-Dimethylacetamide Attenuates Inflammatory Bowel Disease in In Vitro and In Vivo Models. Fortune J Health Sci. 2022;5:499-509. [Content Brief]
