138-41-0
138-41-0
Chemical Structure
Carzenide
Synonym(s): 4-Sulfamoylbenzoic acid
- CAS No.: 138-41-0
- Formula:C7H7NO4S
- Molecular Weight:201.20
IUPAC Name: 4-sulfamoylbenzoic acid
InChIKey: UCAGLBKTLXCODC-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=C(S(=O)(N)=O)C=C1
Biological Activity: Carzenide (4-Sulfamoylbenzoic acid) is the major circulating metabolite of Mafenide (HY-B0614) in plasma. Carzenide is a strong CAII competitive inhibitor. Carzenide can be used in the research of epilepsy and cervical cancer[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Carzenide | 99.45% | Carzenide (4-Sulfamoylbenzoic acid) is the major circulating metabolite of Mafenide (HY-B0614) in plasma. Carzenide is a strong CAII competitive inhibitor. Carzenide can be used in the research of epilepsy and cervical cancer. | ||||||||||||||||||||
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References
- [1]. Weisdorf DJ, et al. Mafenide (Sulfamylon) inhibits plasmin fibrinolytic activity. Thromb Haemost. 1988 Jun 16;59(3):440-4. PMID: 2973151. [Content Brief]
- [2]. Zhang F, et al. Imaging of Carbonic Anhydrase Level in Epilepsy with an Environment-Sensitive Fluorescent Probe. Anal Chem. 2023 Oct 10;95(40):14833-14841. [Content Brief]
- [3]. Abo-Ashour MF, et al. Novel synthesized SLC-0111 thiazole and thiadiazole analogues: Determination of their carbonic anhydrase inhibitory activity and molecular modeling studies. Bioorg Chem. 2019 Jun;87:794-802. [Content Brief]
