1424-27-7
1424-27-7
Chemical Structure
Acetazolamide sodium
- CAS No.: 1424-27-7
- Formula:C4H6N4NaO3S2
- Molecular Weight:245.24
IUPAC Name: N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide, sodium salt
InChIKey: LLRSVYADPZJNGD-UHFFFAOYSA-N
SMILES: CC(NC1=NN=C(S(=O)(N)=O)S1)=O.[Na]
Biological Activity: Acetazolamide sodium is a carbonic anhydrase (CA) IX inhibitor with an IC50 of 30 nM for hCA IX. Acetazolamide sodium has diuretic, antihypertensive and anti-gonococcal activities[1][4][5][6].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Acetazolamide sodium | 99.54% | Acetazolamide sodium is a carbonic anhydrase (CA) IX inhibitor with an IC50 of 30 nM for hCA IX. Acetazolamide sodium has diuretic, antihypertensive and anti-gonococcal activities. | ||||||||||||||||||||
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References
- [1]. Bayat Mokhtari R, et al. Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma. BMC Cancer. 2017 Feb 24;17(1):156. [Content Brief]
- [4]. Kassamali R, et al. Acetazolamide: a forgotten diuretic agent. Cardiol Rev. 2011 Nov-Dec;19(6):276-8. [Content Brief]
- [5]. Jabeen E, et al. Interaction of antihypertensive acetazolamide with nonsteroidal anti-inflammatory drugs. J Photochem Photobiol B. 2013 Aug 5;125:155-63. [Content Brief]
- [6]. Abutaleb NS, et al. In vivo efficacy of acetazolamide in a mouse model of Neisseria gonorrhoeae infection. Microb Pathog. 2022 Mar;164:105454. [Content Brief]
Keywords
