151-73-5
151-73-5
Chemical Structure
Betamethasone disodium phosphate
Synonym(s): Betamethasone 21-phosphate disodium salt; Vista-Methasone
- CAS 番号: 151-73-5
- Formula:C22H28FNa2O8P
- Molecular Weight:516.40
IUPAC Name: sodium 2-((8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl phosphate
InChIKey: PLCQGRYPOISRTQ-LWCNAHDDSA-L
SMILES: C[C@@]12[C@](C[C@@H]([C@]2(O)C(COP(O[Na])(O[Na])=O)=O)C)([H])[C@@]3([H])[C@@]([C@@]4(C(CC3)=CC(C=C4)=O)C)([C@H](C1)O)F
Biological Activity: Betamethasone disodium phosphate (Betamethasone 21-phosphate disodium salt; Vista-Methasone) is a corticosteroid. Betamethasone disodium phosphate is used in research related to inflammatory and immune diseases such as keloids[1].
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
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Betamethasone disodium phosphate | 99.84% | Betamethasone disodium phosphate (Betamethasone 21-phosphate disodium salt; Vista-Methasone) is a corticosteroid. Betamethasone disodium phosphate is used in research related to inflammatory and immune diseases such as keloids. | ||||||||||||||||||||
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Betamethasone disodium phosphate (Standard) | ≥98% | Betamethasone disodium phosphate (Standard) (Betamethasone 21-phosphate disodium salt (Standard); Vista-Methasone (Standard)) is the analytical standard of Betamethasone disodium phosphate. This product is intended for research and analytical applications. Betamethasone disodium phosphate (Betamethasone 21-phosphate disodium salt; Vista-Methasone) is a corticosteroid. Betamethasone disodium phosphate is used in research related to inflammatory and immune diseases such as keloids. | ||||||||||||||||||||
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Betamethasone hydrochloride | Betamethasone hydrochloride is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive activities. Betamethasone hydrochloride accelerates fetal lung maturation and induces gene expression and apoptosis. | |||||||||||||||||||||
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Betamethasone acetate | 99.38% | Betamethasone acetate is a glucocorticoid with prenatal application for preventing respiratory distress syndrome (RDS) in premature infants. Betamethasone acetate exhibits dose-dependent effects on somatic and brain development in offspring when administered prenatally to pregnant rats. Betamethasone acetate can be used for the study of antenatal intervention. | ||||||||||||||||||||
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Betamethasone (Standard) | 99.71% | Betamethasone (Standard) is the analytical standard of Betamethasone. This product is intended for research and analytical applications. Betamethasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive activities. Betamethasone accelerates fetal lung maturation and induces gene expression and apoptosis. | ||||||||||||||||||||
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Dexamethasone acetate (Standard) | 99.76% | Dexamethasone acetate (Standard) (Dexamethasone 21-acetate (Standard)) is the analytical standard of Dexamethasone acetate (HY-14648A). This product is intended for research and analytical applications. Dexamethasone acetate (Dexamethasone 21-acetate) is the acetate form of the glucocorticoid Dexamethasone (HY-14648). Dexamethasone acetate has a longer duration of action than Dexamethasone. Dexamethasone acetate can accumulate at inflammatory sites, in mouse liver and mouse lung via nanostructured lipid carriers. Dexamethasone acetate can be used to prepare topical formulations for studies related to sensorineural hearing loss, γ-carrageenan-induced paw edema, chronic active hepatitis, pulmonary diseases, and inflammation after vitreoretinal surgery. | ||||||||||||||||||||
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Dexamethasone (GMP) | Dexamethasone (Hexadecadrol) (GMP) is Dexamethasone (HY-14648) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Dexamethasone is an agonist of glucocorticoid receptor. | |||||||||||||||||||||
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Dexamethasone phosphate-C2-NH2 | Dexamethasone phosphate-C2-NH2 (Compound 49) is a derivative of Dexamethasone (HY-14648). Dexamethasone phosphate-C2-NH2 can be used for the synthesis of antibody-drug conjugates (ADC) and can be used for the research of cancer. | |||||||||||||||||||||
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Dexamethasone phosphate disodium | 99.94% | Dexamethasone phosphate (Dexamethasone 21-phosphate) disodium is a prodrug form of the glucocorticoid Dexamethasone (HY-14648). Dexamethasone phosphate disodium is produced by introducing a phosphate ester group at the 21-position of the Dexamethasone molecule, forming a salt with sodium ions, thereby significantly improving water solubility. Dexamethasone phosphate disodium inhibits LPS (HY-D1056)-induced degradation of IRAK-1 and IRAK-4, and blocks LPS-induced activation of TRAF6, p-TAK1 and p-JNK. Dexamethasone phosphate disodium inhibits the secretion of RANTES, TGF-β1 and NO, promotes the production of MIP-1α and IL-10, and blocks microglial migration. Dexamethasone phosphate disodium is almost completely converted to Dexamethasone in rat blood, and supports transdermal delivery via iontophoresis. Dexamethasone phosphate disodium can be used in research related to steroid-dependent ulcerative colitis, chemotherapy-induced vomiting, allergic asthma and acute colitis (inflammatory bowel disease). | ||||||||||||||||||||
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Dexamethasone phosphate (Standard) | ≥98% | Dexamethasone phosphate (Standard) (Dexamethasone 21-phosphate (Standard)) is the analytical standard of Dexamethasone phosphate (HY-B1829). This product is intended for research and analytical applications. Dexamethasone phosphate (Dexamethasone 21-phosphate) is a prodrug form of the glucocorticoid Dexamethasone (HY-14648). Dexamethasone phosphate is prepared by introducing a phosphate ester group to the hydroxyl group at position 21 of the Dexamethasone molecule. Dexamethasone phosphate inhibits LPS (HY-D1056)-induced degradation of IRAK-1 and IRAK-4, and blocks LPS-induced activation of TRAF6, p-TAK1 and p-JNK. Dexamethasone phosphate inhibits the secretion of RANTES, TGF-β1 and NO, promotes the production of MIP-1α and IL-10, and blocks microglial migration. Dexamethasone phosphate is almost completely converted to Dexamethasone in rat blood, and supports transdermal delivery via iontophoresis. Dexamethasone phosphate can be used in research related to steroid-dependent ulcerative colitis, chemotherapy-induced vomiting, allergic asthma and acute colitis (inflammatory bowel disease). | ||||||||||||||||||||
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Betamethasone dipropionate impurity 5 | 98.18% | Betamethasone dipropionate impurity 5 is an impurity of Betamethasone dipropionate (HY-13571). Betamethasone dipropionate is a glucocorticoid steroid with anti-inflammatory and immunosuppressive abilities. | ||||||||||||||||||||
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Betamethasone impurity 2 | Betamethasone impurity 2 is an impurity of Betamethasone (HY-13570). | |||||||||||||||||||||
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