1670-87-7
1670-87-7
Chemical Structure
SD-169
- CAS No.: 1670-87-7
- Formula:C9H8N2O
- Molecular Weight:160.18
IUPAC Name: 1H-indole-5-carboxamide
InChIKey: GQMYQEAXTITUAE-UHFFFAOYSA-N
SMILES: O=C(C1=CC2=C(NC=C2)C=C1)N
Biological Activity: SD-169 is an orally active ATP-competitive inhibitor of p38α MAPK, with an IC50 of 3.2 nM. SD-169 also weakly inhibits p38β MAPK with an IC50 of 122 nM. SD-169 prevents the development and progression of diabetes by inhibiting T cell infiltration and activation[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
SD-169 | 99.17% | SD-169 is an orally active ATP-competitive inhibitor of p38α MAPK, with an IC50 of 3.2 nM. SD-169 also weakly inhibits p38β MAPK with an IC50 of 122 nM. SD-169 prevents the development and progression of diabetes by inhibiting T cell infiltration and activation. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
SD-169 (Standard) | ≥98% | SD-169 is an orally active ATP-competitive inhibitor of p38α MAPK, with an IC50 of 3.2 nM. SD-169 also weakly inhibits p38β MAPK with an IC50 of 122 nM. SD-169 prevents the development and progression of diabetes by inhibiting T cell infiltration and activation. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.89
HY-59302Indole-5-carboxylic acid, 98% -
Similarity Score 0.89
HY-W0154201H-Indole-6-carboxylic acid -
Similarity Score 0.86
HY-W016739Methyl 1H-indole-6-carboxylate -
Similarity Score 0.81
HY-W0075091H-Indol-5-amine -
Similarity Score 0.81
HY-W0015846-Aminoindole -
Similarity Score 0.79
HY-W0019725-Methylindole -
Similarity Score 0.79
HY-W0073496-Methyl-1H-indole -
Similarity Score 0.79
HY-302365-Bromoindole -
Similarity Score 0.79
HY-W0073845-Chloroindole -
Explore the MedChemAI to find more analogs
