1670-87-7
1670-87-7
Chemical Structure
SD-169
- CAS No.: 1670-87-7
- Formula:C9H8N2O
- Molecular Weight:160.18
IUPAC Name: 1H-indole-5-carboxamide
InChIKey: GQMYQEAXTITUAE-UHFFFAOYSA-N
SMILES: O=C(C1=CC2=C(NC=C2)C=C1)N
Biological Activity: SD-169 is an orally active ATP-competitive inhibitor of p38α MAPK, with an IC50 of 3.2 nM. SD-169 also weakly inhibits p38β MAPK with an IC50 of 122 nM. SD-169 prevents the development and progression of diabetes by inhibiting T cell infiltration and activation[1].
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SD-169 | 99.17% | SD-169 is an orally active ATP-competitive inhibitor of p38α MAPK, with an IC50 of 3.2 nM. SD-169 also weakly inhibits p38β MAPK with an IC50 of 122 nM. SD-169 prevents the development and progression of diabetes by inhibiting T cell infiltration and activation. | ||||||||||||||||||||
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SD-169 (Standard) | ≥98% | SD-169 is an orally active ATP-competitive inhibitor of p38α MAPK, with an IC50 of 3.2 nM. SD-169 also weakly inhibits p38β MAPK with an IC50 of 122 nM. SD-169 prevents the development and progression of diabetes by inhibiting T cell infiltration and activation. | ||||||||||||||||||||
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