199331-35-6
199331-35-6
Chemical Structure
Dehydroglyasperin C
- CAS No.: 199331-35-6
- Formula:C21H22O5
- Molecular Weight:354.40
IUPAC Name: 4-(7-hydroxy-5-methoxy-6-(3-methylbut-2-en-1-yl)-2H-chromen-3-yl)benzene-1,3-diol
InChIKey: UACNRZUVCUEUPY-UHFFFAOYSA-N
SMILES: OC1=CC=C(C2=CC3=C(OC)C(C/C=C(C)\C)=C(O)C=C3OC2)C(O)=C1
Biological Activity: Dehydroglyasperin C, a isoflavone, is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C has antioxidant, neuroprotective, cancer chemopreventive, and anti-inflammatory activities[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Dehydroglyasperin C | 99.12% | Dehydroglyasperin C, a isoflavone, is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C has antioxidant, neuroprotective, cancer chemopreventive, and anti-inflammatory activities. | ||||||||||||||||||||
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Glicophenone | Glicophenone is an antibacterial agent with MICs of both 32 μg/mL against MRSA OM481, MRSA OM505, MRSA OM584, MRSA OM623 and MSSA 209P. | |||||||||||||||||||||
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3,4-Didehydroglabridin | 3,4-Didehydroglabridin is a natural product that can be found in licorice. 3,4-Didehydroglabridin exhibits protective activities against carbon tetrachloride-induced HepG2 cells injury. 3,4-Didehydroglabridin has the potential for the research of liver injury. | |||||||||||||||||||||
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Haginin D | Haginin D is an isoflavonoid phenolic compound found in the stems of Lespedeza homoloba. Haginin D suppresses lipid peroxidation in rat brain homogenates. Haginin D scavenges superoxide anion free radicals. Haginin D can be used in studies of oxidative damage and allergic reactions. | |||||||||||||||||||||
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Neorauflavene | Neorauflavene is a phenolic neorautanenia isoflavanoid isolated from Neorautanenia edulis. Neorauflavene shows antibacterial activities against E. faecalis, S. suis, S. agalactiae, P. aeruginosa, B. subtilis, and R. anatipestifer. | |||||||||||||||||||||
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Dehydroglyasperin D | Dehydroglyasperin D inhibits rat and human Aldose Reductase (AR) (IC50: 62.4 μM and 176.2 μM respectively). Dehydroglyasperin D has anti-obesity, antioxidant effects. Dehydroglyasperin D shows anti-inflammatory activity by inhibiting COX-2 expression and the MLK3 signaling pathway. Dehydroglyasperin D also inhibits melanin synthesis. Dehydroglyasperin D is a prenylated flavonoid that can be isolated from Glycyrrhiza uralensi. | |||||||||||||||||||||
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Glyasperin D | Glyasperin D is a flavonoid isolated from Glycyrrhiza uralensis, and possesses weaker anti-Helicobacter pylori activity. | |||||||||||||||||||||
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Odoriflavene | Odoriflavene is a phenolic compound found in the root heartwood of Dalbergia odorifera T. Chen (Leguminosae). | |||||||||||||||||||||
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Haginin A | Haginin A (compound 3）can be isolated from the EtOAc fraction of Lespedeza cyrtobotrya. Haginin A has radical scavenging activity with IC50 values of 9.0 μM and 37.7 μM in the ABTS system and DPPH system, respectively. | |||||||||||||||||||||
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Glyasperin C | 98.85% | Glyasperin C is a potent and reversible noncompetitive inhibitor of neuraminidase with an IC50 of 20% at 200 μM. Glyasperin C is a polyphenol isolated from the roots of Glycyrrhiza uralensis. | ||||||||||||||||||||
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Bidwillol A | Bidwillol A is a Flavonoids product that can be isolated from the herbs of Erythrina arborescens. | |||||||||||||||||||||
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References
- [1]. Hyo Jung Kim, et al. Dehydroglyasperin C, a component of liquorice, attenuates proliferation and migration induced by platelet-derived growth factor in human arterial smooth muscle cells. Br J Nutr. 2013 Aug 28;110(3):391-400. [Content Brief]
- [2]. Ji Hoon Lee, et al. Dehydroglyasperin C suppresses TPA-induced cell transformation through direct inhibition of MKK4 and PI3K. Mol Carcinog. 2016 May;55(5):552-62. [Content Brief]
- [3]. Ji Yeon Seo, et al. Dehydroglyasperin C isolated from licorice caused Nrf2-mediated induction of detoxifying enzymes. J Agric Food Chem. 2010 Feb 10;58(3):1603-8. [Content Brief]
