2010986-87-3
2010986-87-3
Chemical Structure
VHL Ligand 14
- CAS No.: 2010986-87-3
- Formula:C25H34N4O4S
- Molecular Weight:486.63
IUPAC Name: (2S,4R)-1-((S)-2-acetamido-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide
InChIKey: JAHUHEDUDMTTTF-COWZOJLOSA-N
SMILES: O=C([C@H]1N(C([C@@H](NC(C)=O)C(C)(C)C)=O)C[C@H](O)C1)N[C@H](C2=CC=C(C3=C(C)N=CS3)C=C2)C
Biological Activity: VHL Ligand 14 (Compound 11) is a VHL ligand for design of PROTAC estrogen receptor α (ERα) degraders, with a binding affinity IC50 of 196 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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VHL Ligand 14 | 99.93% | VHL Ligand 14 (Compound 11) is a VHL ligand for design of PROTAC estrogen receptor α (ERα) degraders, with a binding affinity IC50 of 196 nM. | ||||||||||||||||||||
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References
Keywords
