20127-63-3
Chemical Structure
1-Formyl-beta-carboline
- CAS No.: 20127-63-3
- Formula:C12H8N2O
- Molecular Weight:196.21
IUPAC Name: 9H-pyrido[3,4-b]indole-1-carbaldehyde
InChIKey: CHQBGSRZQLMDEX-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C3=C(C(=NC=C3)C=O)N2
Biological Activity: 1-Formyl-beta-carboline is an alkaloid with inhibitory activity against Newcastle disease virus (NDV). 1-Formyl-beta-carboline can effectively inhibit different genotypes of NDV with IC50 values within 10 μM, and its inhibition rate is more than 90% at a concentration of 20 μM. 1-Formyl-beta-carboline mainly exerts its effects by inhibiting the adsorption and entry processes in the NDV life cycle. 1-Formyl-beta-carboline has been identified as a novel HN inhibitor that can directly interact with the NDV HN protein and affect the adsorption of NDV. 1-Formyl-beta-carboline also inhibits the entry of NDV by inhibiting the PI3K/Akt signaling pathway rather than the ERK pathway[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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1-Formyl-beta-carboline | 99.27% | 1-Formyl-beta-carboline is an alkaloid with inhibitory activity against Newcastle disease virus (NDV). 1-Formyl-beta-carboline can effectively inhibit different genotypes of NDV with IC50 values within 10 μM, and its inhibition rate is more than 90% at a concentration of 20 μM. 1-Formyl-beta-carboline mainly exerts its effects by inhibiting the adsorption and entry processes in the NDV life cycle. 1-Formyl-beta-carboline has been identified as a novel HN inhibitor that can directly interact with the NDV HN protein and affect the adsorption of NDV. 1-Formyl-beta-carboline also inhibits the entry of NDV by inhibiting the PI3K/Akt signaling pathway rather than the ERK pathway. | ||||||||||||||||||||
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