2079069-01-3
Chemical Structure
Casein Kinase inhibitor A86
- CAS No.: 2079069-01-3
- Formula:C18H25FN6
- Molecular Weight:344.43
IUPAC Name: (1r,4r)-N1-(4-(5-(cyclopropylmethyl)-1-methyl-1H-pyrazol-4-yl)-5-fluoropyrimidin-2-yl)cyclohexane-1,4-diamine
InChIKey: YSPIHUWHLMNFOV-JOCQHMNTSA-N
SMILES: N[C@H]1CC[C@H](NC2=NC=C(F)C(C3=C(CC4CC4)N(C)N=C3)=N2)CC1
Biological Activity: Casein Kinase inhibitor A86 is a potent and orally active casein kinase 1α (CK1α) inhibitor. Casein Kinase inhibitor A86 also inhibits of CDK7 (TFIIH) and CDK9 (P-TEFb). Casein Kinase inhibitor A861 induces leukemia cell apoptosis, and has potent anti-leukemic activities[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Casein Kinase inhibitor A86 | 99.26% | Casein Kinase inhibitor A86 is a potent and orally active casein kinase 1α (CK1α) inhibitor. Casein Kinase inhibitor A86 also inhibits of CDK7 (TFIIH) and CDK9 (P-TEFb). Casein Kinase inhibitor A861 induces leukemia cell apoptosis, and has potent anti-leukemic activities. | ||||||||||||||||||||
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Keywords
