2136270-56-7
2136270-56-7
Chemical Structure
SPOP-IN-1
- CAS No.: 2136270-56-7
- Formula:C26H31N7O2S
- Molecular Weight:505.64
InChIKey: CQWPQOGWIPGPOA-UHFFFAOYSA-N
SMILES: O=C(C1=CC2=C(N(CCC3=CC=CS3)C1=N)N=C4C(C)=CC=CN4C2=O)NCCN5CCN(CC5)C
Biological Activity: SPOP-IN-1 is a selective SPOP E3 ubiquitin ligase inhibitor. SPOP-IN-1 leads to the accumulation of tumor suppressors PTEN and DUSP7 and decreased levels of phosphorylated AKT and ERK in clear-cell renal cell carcinoma[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SPOP-IN-1 | 99.71% | SPOP-IN-1 is a selective SPOP E3 ubiquitin ligase inhibitor. SPOP-IN-1 leads to the accumulation of tumor suppressors PTEN and DUSP7 and decreased levels of phosphorylated AKT and ERK in clear-cell renal cell carcinoma. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.73
HY-122615SPOP-IN-6b -
Similarity Score 0.73
HY-122615ASPOP-IN-6b hydrochloride -
Similarity Score 0.51
HY-145840Pol I-IN-1 -
Similarity Score 0.50
HY-107749ML 190 -
Similarity Score 0.47
HY-14375CB 300919 -
Similarity Score 0.46
HY-124635BC-54 -
Similarity Score 0.46
HY-12484BMH-21 -
Similarity Score 0.45
HY-128759DYRKs-IN-2 -
Similarity Score 0.45
HY-146411microRNA-21-IN-1 -
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